Wang Tian School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation, Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong Yantai University Biography Publications Institution JoVE Articles Wang Tian has not added a biography. If you are Wang Tian and would like to personalize this page please email our Author Liaison for assistance. Publications Biofluid Biomarkers for Alzheimer's Disease Frontiers in Aging Neuroscience. 2024 | Pubmed ID: 38659704 Antinociceptive Effects of Carbidopa Levodopa on Normal Rats and Parkinson's Disease Mice Pakistan Journal of Pharmaceutical Sciences. Sep, 2023 | Pubmed ID: 37869925 Escin Avoids Hemorrhagic Transformation in Ischemic Stroke by Protecting BBB Through the AMPK/Cav-1/MMP-9 Pathway Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. Nov, 2023 | Pubmed ID: 37716034 LAR Downregulation Protects the Astrocytic U251 and Cocultured SH-SY5Y Cells in a Rotenone-Induced Parkinson's Disease Cell Model International Journal of Molecular Sciences. Jul, 2023 | Pubmed ID: 37446291 Effects of Natural Products on Skin Inflammation Caused by Abnormal Hormones Secreted by the Adrenal Gland Frontiers in Pharmacology. 2023 | Pubmed ID: 37205913 The Effect of Triple Reuptake Inhibitor Toludesvenlafaxine on Neurological Function in Cerebral Ischemic Rats Frontiers in Pharmacology. 2023 | Pubmed ID: 37153779 Escin Alleviates Stress-induced Intestinal Dysfunction to Protect Brain Injury by Regulating the Gut-brain Axis in Ischemic Stroke Rats International Immunopharmacology. Feb, 2023 | Pubmed ID: 36608442 Administration of Huperzine A Microspheres Ameliorates Myocardial Ischemic Injury Via α7nAChR-dependent JAK2/STAT3 Signaling Pathway European Journal of Pharmacology. Feb, 2023 | Pubmed ID: 36563953 Rosmarinic Acid Attenuates Rotenone-Induced Neurotoxicity in SH-SY5Y Parkinson's Disease Cell Model Through Abl Inhibition Nutrients. Aug, 2022 | Pubmed ID: 36079767 Integrated Systematic Pharmacology Analysis and Experimental Validation to Reveal the Mechanism of Action of Semen Aesculi on Inflammatory Bowel Diseases Journal of Ethnopharmacology. Nov, 2022 | Pubmed ID: 35985613 The Etiology of Poststroke-depression: a Hypothesis Involving HPA Axis Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. Jul, 2022 | Pubmed ID: 35643064 Meldonium Ameliorates Hypoxia-Induced Lung Injury and Oxidative Stress by Regulating Platelet-Type Phosphofructokinase-Mediated Glycolysis Frontiers in Pharmacology. 2022 | Pubmed ID: 35450040 Continuous Activation of Dopamine Receptors Alleviates LPS-Induced Liver Injury in Mice Via β-arrestin2 Dependent Akt/NF-κB Pathway Frontiers in Pharmacology. 2022 | Pubmed ID: 35359858 Dopamine, a Co-regulatory Component, Bridges the Central Nervous System and the Immune System Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. Jan, 2022 | Pubmed ID: 34847478 Is It Possible to Estimate the Bioequivalence Between Parenteral and Enteral Formulations of Escin? Current Reviews in Clinical and Experimental Pharmacology. 2022 | Pubmed ID: 33687899 The Use of Herbal Medicines for the Prevention of Glucocorticoid-Induced Osteoporosis Frontiers in Endocrinology. 2021 | Pubmed ID: 34867788 Dopamine Receptor Agonist Rotigotine-loaded Microspheres Ameliorates Sexual Function Deteriorated by Fluoxetine in Depression Rats ASN Neuro. 2021 | Pubmed ID: 34724850 Rotigotine-loaded Microspheres Exerts the Antinociceptive Effect Via Central Dopaminergic System European Journal of Pharmacology. Nov, 2021 | Pubmed ID: 34464604 Ginsenoside Rg3 Exerts a Neuroprotective Effect in Rotenone-induced Parkinson's Disease Mice Via Its Anti-oxidative Properties European Journal of Pharmacology. Oct, 2021 | Pubmed ID: 34391769 Ginsenoside Rg2 Ameliorates Brain Injury After Intracerebral Hemorrhage in a Rat Model of Preeclampsia Reproductive Sciences (Thousand Oaks, Calif.). Dec, 2021 | Pubmed ID: 34270001 Lipopolysaccharide/D-galactosamine-induced Acute Liver Injury Could Be Attenuated by Dopamine Receptor Agonist Rotigotine Via Regulating NF-κB Signaling Pathway International Immunopharmacology. Jul, 2021 | Pubmed ID: 34162160 Glucocorticoid-Like Activity of Escin: A New Mechanism for an Old Drug Drug Design, Development and Therapy. 2021 | Pubmed ID: 33658760 Escin Ameliorates the Impairments of Neurological Function and Blood Brain Barrier by Inhibiting Systemic Inflammation in Intracerebral Hemorrhagic Mice Experimental Neurology. Mar, 2021 | Pubmed ID: 33309746 Antinociceptive Effects of Rotigotine-loaded Microspheres and Its Synergistic Interactions with Analgesics in Inflammatory Pain in Rats European Journal of Pharmacology. Jan, 2021 | Pubmed ID: 33160937 The Effect of Rotigotine Extended-Release Microspheres Alone or With Celecoxib on the Inflammatory Pain Frontiers in Pharmacology. 2020 | Pubmed ID: 33192533 Inhibition of Notch Enhances the Anti-atherosclerotic Effects of LXR Agonists While Reducing Fatty Liver Development in ApoE-deficient Mice Toxicology and Applied Pharmacology. Nov, 2020 | Pubmed ID: 32853627 Severe Acute Lung Injury Related to COVID-19 Infection: A Review and the Possible Role for Escin Journal of Clinical Pharmacology. Jul, 2020 | Pubmed ID: 32441805 Rosmarinic Acid Protects Against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Dopaminergic Neurotoxicity in Zebrafish Embryos Toxicology in Vitro : an International Journal Published in Association with BIBRA. Jun, 2020 | Pubmed ID: 32147576 Neuroprotective Effects of Danshensu on Rotenone-induced Parkinson's Disease Models in Vitro and in Vivo BMC Complementary Medicine and Therapies. Jan, 2020 | Pubmed ID: 32020857 Network Pharmacology Based Research on the Combination Mechanism Between Escin and Low Dose Glucocorticoids in Anti-rheumatoid Arthritis Frontiers in Pharmacology. 2019 | Pubmed ID: 30967782 Effects of Rotigotine and Rotigotine Extended-release Microsphere Therapy on Myocardial Ischemic Injury in Mice European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Jun, 2019 | Pubmed ID: 30959104 Neuroprotective Effects of Danshensu in Parkinson's Disease Mouse Model Induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Behavioural Pharmacology. Feb, 2019 | Pubmed ID: 29847337 Hydroxysafflor Yellow A Attenuates Lipopolysaccharide-Induced Neurotoxicity and Neuroinflammation in Primary Mesencephalic Cultures Molecules (Basel, Switzerland). May, 2018 | Pubmed ID: 29783643 Activation of Dopamine D1 Receptor Decreased NLRP3-mediated Inflammation in Intracerebral Hemorrhage Mice Journal of Neuroinflammation. Jan, 2018 | Pubmed ID: 29301581 Ginsenoside Rg1 Attenuates Adjuvant-induced Arthritis in Rats Via Modulation of PPAR-γ/NF-κB Signal Pathway Oncotarget. Aug, 2017 | Pubmed ID: 28903427 Osteogenic Potency of Dedifferentiated Fat Cells Isolated from Elderly People with Osteoporosis Experimental and Therapeutic Medicine. Jul, 2017 | Pubmed ID: 28672891 Hydroxysafflor Yellow A Improves Motor Dysfunction in the Rotenone-Induced Mice Model of Parkinson's Disease Neurochemical Research. May, 2017 | Pubmed ID: 28097465 Huatuo Zaizao Pill Promotes Functional Recovery and Neurogenesis After Cerebral Ischemia-reperfusion in Rats BMC Complementary and Alternative Medicine. Jan, 2017 | Pubmed ID: 28056920 Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment Ameliorate Acetaminophen-Induced Liver Injury in Mice Via Central Cholinergic System Regulation The Journal of Pharmacology and Experimental Therapeutics. Nov, 2016 | Pubmed ID: 27535978 Evaluation of the Antidepressant Activity, Hepatotoxicity and Blood Brain Barrier Permeability of Methyl Genipin Molecules (Basel, Switzerland). Jul, 2016 | Pubmed ID: 27438811 Neurological Function Following Cerebral Ischemia/reperfusion is Improved by the Ruyi Zhenbao Pill in a Rats Biomedical Reports. Feb, 2016 | Pubmed ID: 26893831 Oral Administration of Escin Inhibits Acute Inflammation and Reduces Intestinal Mucosal Injury in Animal Models Evidence-based Complementary and Alternative Medicine : ECAM. 2015 | Pubmed ID: 26199634 Coadministration of Hydroxysafflor Yellow A with Levodopa Attenuates the Dyskinesia Physiology & Behavior. Aug, 2015 | Pubmed ID: 25914172 Ferulic Acid Ameliorates Nerve Injury Induced by Cerebral Ischemia in Rats Experimental and Therapeutic Medicine. Mar, 2015 | Pubmed ID: 25667662 A Potential Target for the Treatment of Parkinson's Disease: Effect of Lateral Habenula Lesions Parkinsonism & Related Disorders. Nov, 2014 | Pubmed ID: 25219971 Protective Effects of Escin Against Indomethacin-induced Gastric Ulcer in Mice Toxicology Mechanisms and Methods. Dec, 2014 | Pubmed ID: 25137224 Yanshu Spraying Agent, a Traditional Chinese Medicine, Relieves Chronic Pharyngitis in Animals by Anti-inflammatory and Antibacterial Effects Experimental and Therapeutic Medicine. Apr, 2014 | Pubmed ID: 24669264 A Novel Approach to Medical Countermeasures Against Organophosphorus Compound Toxicity Biomedical Reports. Nov, 2013 | Pubmed ID: 24649050 Effects of the Coadministration of Huatuo Zaizao Pills and Aspirin on Hemorrheology and Blood Coagulation in Rabbits Biomedical Reports. May, 2013 | Pubmed ID: 24648968 Inhibition of SPLA₂-IIA Prevents LPS-induced Neuroinflammation by Suppressing ERK1/2-cPLA₂α Pathway in Mice Cerebral Cortex PloS One. 2013 | Pubmed ID: 24130900 Ginsenoside Rg1 Exerts Synergistic Anti-inflammatory Effects with Low Doses of Glucocorticoids in Vitro Fitoterapia. Dec, 2013 | Pubmed ID: 24035860 Neuroprotective Effect of Hydroxysafflor Yellow A on 6-hydroxydopamine-induced Parkinson's Disease in Rats European Journal of Pharmacology. Aug, 2013 | Pubmed ID: 23791614 The Effects of Huperzine A on Gastrointestinal Acetylcholinesterase Activity and Motility After Single and Multiple Dosing in Mice Experimental and Therapeutic Medicine. Mar, 2013 | Pubmed ID: 23403922 Hypersensitivity Reaction Studies of a Polyethoxylated Castor Oil-free, Liposome-based Alternative Paclitaxel Formulation Molecular Medicine Reports. Mar, 2013 | Pubmed ID: 23291923 Anti-inflammatory Activity of Yanshu Spraying Agent in Animal Models Experimental and Therapeutic Medicine. Jan, 2013 | Pubmed ID: 23251244 Sodium Aescinate Ameliorates Liver Injury Induced by Methyl Parathion in Rats Experimental and Therapeutic Medicine. May, 2012 | Pubmed ID: 22969975 Potent Anti-inflammatory Agent Escin Does Not Affect the Healing of Tibia Fracture and Abdominal Wound in an Animal Model Experimental and Therapeutic Medicine. Apr, 2012 | Pubmed ID: 22969961 Steady and Fluctuant Methods of Inhibition of Acetylcholinesterase Differentially Regulate Neurotrophic Factors in the Hippocampus of Juvenile Mice Experimental and Therapeutic Medicine. Feb, 2012 | Pubmed ID: 22969880 Down-regulation of P-glycoprotein Expression Contributes to an Increase in Danshensu Accumulation in the Cerebral Ischemia/reperfusion Brain Molecular Medicine Reports. Mar, 2012 | Pubmed ID: 22134431 Protective Effect of Aescin from the Seeds of Aesculus Hippocastanum on Liver Injury Induced by Endotoxin in Mice Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. Nov, 2011 | Pubmed ID: 21802269 The Potent Anti-inflammatory Agent Escin Does Not Increase Corticosterone Secretion and Immune Cell Apoptosis in Mice Fitoterapia. Sep, 2011 | Pubmed ID: 21596110 Escin Attenuates Cerebral Edema Induced by Acute Omethoate Poisoning Toxicology Mechanisms and Methods. Jun, 2011 | Pubmed ID: 21417632 The Role of P-Glycoprotein in Transport of Danshensu Across the Blood-Brain Barrier Evidence-based Complementary and Alternative Medicine : ECAM. 2011 | Pubmed ID: 21318104 Protective Effect of Sodium Aescinate on Lung Injury Induced by Methyl Parathion Human & Experimental Toxicology. Oct, 2011 | Pubmed ID: 21177729 Escin Attenuates Acute Lung Injury Induced by Endotoxin in Mice European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Jan, 2011 | Pubmed ID: 21040784 Escin Exerts Synergistic Anti-inflammatory Effects with Low Doses of Glucocorticoids in Vivo and in Vitro Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. Feb, 2011 | Pubmed ID: 20850956 Protective Effects of Danshensu on Liver Injury Induced by Omethoate in Rats Toxicology Mechanisms and Methods. Oct, 2010 | Pubmed ID: 20843270 Escin Attenuates Cognitive Deficits and Hippocampal Injury After Transient Global Cerebral Ischemia in Mice Via Regulating Certain Inflammatory Genes Neurochemistry International. Sep, 2010 | Pubmed ID: 20466027 Study on the Structure-function Relationship of 20(S)-panaxadiol and Its Epimeric Derivatives in Myocardial Injury Induced by Isoproterenol Fitoterapia. Oct, 2010 | Pubmed ID: 20398743 Reduced Glutathione Attenuates Liver Injury Induced by Methyl Parathion in Rats Toxicology Mechanisms and Methods. Feb, 2010 | Pubmed ID: 20100039 Effects of Escin on Acute Inflammation and the Immune System in Mice Pharmacological Reports : PR. 2009 | Pubmed ID: 19815952 A Rat Model of Middle Cerebral Artery Occlusion/Reperfusion without Damaging the Anatomical Structure of Cerebral Vessels Zhang Jiren1, Jia Xue2, Sun Yufei2, Li Huiwen2, Yang Jian1, Qi Shilei1, Zhao Dongman1, Xie Lei1, Jia Mingming1, Wang Tian2, Zhang Pinyuan1 1Department of Neurosurgery, The Third Hospital of Hebei Medical University, 2School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation, Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University JoVE 66635 Neuroscience
A Rat Model of Middle Cerebral Artery Occlusion/Reperfusion without Damaging the Anatomical Structure of Cerebral Vessels Zhang Jiren1, Jia Xue2, Sun Yufei2, Li Huiwen2, Yang Jian1, Qi Shilei1, Zhao Dongman1, Xie Lei1, Jia Mingming1, Wang Tian2, Zhang Pinyuan1 1Department of Neurosurgery, The Third Hospital of Hebei Medical University, 2School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation, Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University JoVE 66635 Neuroscience